Harnessing viral footprints in circulating free DNA (cfDNA) for early cancer detection: A focus on liquid‐biopsy‐based screening

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This review discusses cfDNA's potential in identifying viral signatures in cancer patients, suggesting innovative screening methods.

Early detection of virus-driven cancers can greatly improve patient outcomes, showcasing the need for enhanced screening methods.
The integration of cfDNA analysis using viral markers provides a promising non-invasive approach for cancer diagnosis.
Understanding oncogenic viruses' role in malignancy progression allows for more targeted cancer monitoring strategies.
Emphasizing the clinical relevance, cfDNA-based screening could transform personalized cancer management.

Amponsah et al. (2025) studied this question.

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