Evolutionary Trajectories in Phytopharmaceutical Drug Development: From Ethnopharmacology to Polypharmacology

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This review uncovers how ethnopharmacology informs multi-target therapies in phytopharmaceuticals, suggesting a need for integrated approaches.

The review reveals a critical pathway in drug development, transitioning from traditional ethnopharmacology to modern polypharmacology.
Key findings indicate that therapeutic efficacy stems from synergistic actions of multiple constituents acting on various biological targets.
This observational analysis explores methodologies combining traditional knowledge with modern pharmacological techniques in drug discovery.
The implications point to the potential for novel multi-target phytopharmaceuticals, while highlighting challenges in this integrative field.

Blessymole K. Alex (2025) studied this question.

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This review uncovers how ethnopharmacology informs multi-target therapies in phytopharmaceuticals, suggesting a need for integrated approaches.