From biomarkers to drug delivery: advances in extracellular vesicles in cancer diagnosis and targeted therapy

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Extracellular vesicles serve as non-invasive biomarkers for cancer diagnosis, improving sensitivity and specificity.
Tumor-derived EVs facilitate cancer progression by transferring oncogenic materials, enhancing therapeutic challenges.
Engineered EVs loaded with therapeutic agents show improved tumor targeting and reduced off-target effects in preclinical models.
Surface modifications to EVs enhance their specificity in targeting cancer cells, potentially boosting therapeutic efficacy.

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This review demonstrates the diagnostic potential of extracellular vesicles and suggests their roles in drug delivery and therapy for cancer.

Lindqvist et al. (2025) studied this question.

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This review demonstrates the diagnostic potential of extracellular vesicles and suggests their roles in drug delivery and therapy for cancer.