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September 10, 2025eJHaemOpen Access

Late‐Onset Invasive Aspergillosis With Pituitary Involvement and Dysfunction Following CD19 Chimeric Antigen Receptor T‐Cell Therapy

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Authors

DIDaisuke IkedaTNT. NaganoTKTakumi Kondo

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Overview

Case highlights persistent risk of late-onset fungal infections in patients after CAR T-cell therapy.

Key Points

  • Late-onset invasive aspergillosis can occur up to one year after CD19 CAR T-cell therapy.
  • The case emphasizes the importance of monitoring for fungal infections beyond the initial post-infusion period.
  • Continued vigilance and tailored antifungal strategies are crucial to manage these infections effectively.
  • This illustrates the risks associated with delayed immune reconstitution after CAR T-cell infusion.

Cite This Study

Ikeda et al. (2025) studied this question.

synapsesocial.com/papers/68c23abeb210217d647813bchttps://doi.org/10.1002/jha2.70138
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