September 10, 2025PLOS Global Public HealthOpen Access

The acceptability, safety, and performance of primary cervical screening through self-collected vaginal samples in an urban teaching hospital antenatal clinic setting

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Cross-sectional study reveals high acceptability and safety of self-collected samples in antenatal care, suggesting improved screening rates.

Self-collection for HPV testing in pregnant women demonstrates high acceptance, with 99.0% willing to use it again.
Of the 1,603 participants, 99.6% agreed to self-collect, with a successful completion rate of 98.6%.
HPV prevalence in the study population was 6.3%, mainly involving non-HPV16/18 types, indicating diverse infection patterns.
Integration of self-collection into antenatal care may enhance cervical cancer screening rates, addressing under-screened populations.

Khoo et al. (2025) studied this question.

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Cross-sectional study reveals high acceptability and safety of self-collected samples in antenatal care, suggesting improved screening rates.