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September 10, 2025Open Access

Digital phenotyping using wearable-determined physical behaviors and machine learning to detect depression and anxiety in a general population

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Authors

ASAlireza SamehLNLaura NauhaMSMarjo Seppänen

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Overview

Digital phenotyping identifies depression and anxiety in a general population using wearable data, highlighting potential physical behavior metrics.

Key Points

  • Accuracy of 66%-72% and AUC of 66%-70% were achieved using machine learning models, particularly with random forest.
  • Physical behavior metrics such as wake up time and activity intensity emerged as key predictors of depression and anxiety.
  • Participants wore accelerometers for 14 days to collect data, allowing for a comprehensive analysis of physical behaviors.
  • Findings suggest wearable-derived metrics may effectively differentiate individuals with and without depression and anxiety symptoms.

Cite This Study

Sameh et al. (2025) studied this question.

synapsesocial.com/papers/68c23a74b210217d64781109https://doi.org/10.1101/2025.09.01.25334782
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Using smartphone-tracked behavioural markers to recognize depression and anxiety symptoms: Digital phenotyping in the Netherlands Study of Depression and Anxiety (Preprint)2025
  2. 2Assessing the feasibility of large-scale digital sensing for depression and anxiety: The Digital Mental Health Study2025
  3. 3Mobile Technology for Just-in-Time Prediction of Depression: A Scoping Review2025
  4. 4Recommendations for digital phenotyping using consumer grade wearable devices among people with severe mental illness: lessons from a systematic review of the literature2025
  5. 5Harnessing Digital Phenotyping for Early Self-Detection of Psychological Distress2025