September 10, 2025Open Access

Aqueous Basella alba Mitigates Cyclosporine-Induced Nephrotoxicity in Wistar Rats: Relevance in Adjuvant Therapy

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Aqueous Basella alba extract reduces nephrotoxicity impacts in Wistar rats, suggesting adjuvant therapy potential.

Treatment with Basella alba extract significantly reduced markers of nephrotoxicity in Wistar rats.
Aqueous Basella alba extract demonstrated notable protective effects on oxidative stress and inflammation.
Histological analysis showed near-normal kidney architecture after treatment with Basella alba extract.
The highest dosage of Basella alba extract provided the most effective mitigation of kidney damage.

Imafidon et al. (2025) studied this question.

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