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September 5, 2025Journal of Clinical Pharmacy and TherapeuticsOpen Access

Real‐World Data Analysis of Vascular and Lymphatic Adverse Events Associated With Antitumor Angiogenesis Drugs: A WHO‐VigiAccess Study

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Authors

YZYue Xin ZuShandong University of Traditional Chinese MedicineLDLuqi DaiThe First Affiliated Hospital, Sun Yat-sen UniversityPMPeng Meng

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Implication

Observational analysis identifies specific vascular and lymphatic adverse events in patients, indicating potential risks linked to antiangiogenic therapy.

Key Points

  • Antiangiogenic therapy is linked to significant vascular and lymphatic adverse events that require careful monitoring.
  • Disproportionality analysis revealed drug-specific risks, with hypertension and hemorrhage being major concerns.
  • Using data from WHO‐VigiAccess ensured a comprehensive evaluation of FDA-approved agents in real-world settings.
  • Findings highlight the need for personalized clinical use of antiangiogenic drugs to improve patient safety.

Cite This Study

Zu et al. (2025) studied this question.

synapsesocial.com/papers/68c23a74b210217d64780183https://doi.org/10.1155/jcpt/9501977
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