This study demonstrates urolithin C's effectiveness in lowering serum uric acid and protecting kidneys, highlighting its role in managing hyperuricemia.
Key Points
Urolithin C significantly lowered serum uric acid levels in hyperuricemia mice, indicating its effectiveness in treatment.
The study discovered that urolithin C reduced renal oxidative stress and fibrosis through inhibition of reactive oxygen species production.
Urolithin C enhanced renal uric acid excretion while targeting p38/ERK MAPK pathway, showcasing its therapeutic mechanism.
Results suggest urolithin C as a promising food-derived treatment option for managing hyperuricemia and renal protection.