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September 5, 2025Frontiers in MedicineOpen Access

Subacute liver failure caused by hyperthyroidism and complicated by drugs: a case report and review of the literature

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Authors

YHYingyong HouMTMelinda TongYYYang Yu

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Overview

Case report details acute liver injury in a patient with hyperthyroidism, suggesting multidisciplinary management is crucial.

Key Points

  • Severe liver dysfunction was observed due to hyperthyroidism and drug-induced liver injury, complicating treatment.
  • Elevated liver enzymes and bilirubin were documented, requiring innovative therapeutic approaches involving glucocorticoids.
  • Multidisciplinary management was critical for addressing overlapping etiologies of liver injury in this case report.
  • Radioactive iodine treatment ultimately stabilized thyroid and liver function, demonstrating a successful intervention.

Cite This Study

Hou et al. (2025) studied this question.

synapsesocial.com/papers/68c23a2cb210217d6477f4c3https://doi.org/10.3389/fmed.2025.1629957
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Case Report: A case of thyroid storm with lower FT3 and FT4 levels accompanied by acute liver failure2025 · 3 citations
  2. 2Thyroid storm with concurrent autoimmune hepatitis: a case report on diagnostic challenges and the role of therapeutic plasma exchange2025
  3. 3A case report: Hypothyreosis complicated by rhabdomyolysis and acute renal injury2025
  4. 4STORM TO SILENCE: VARIOUS ADVERSITIES AND MANAGEMENT OF HYPERTHYROIDISM (CASE SERIES FROM A TERTIARY CARE CENTRE)2025
  5. 5Undiagnosed Hypothyroidism as a Contributor to Cryptogenic Cirrhosis: A Case Report and Diagnostic Perspective2025