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September 5, 2025Current Obesity ReportsOpen Access

Adipose Tissue, at the Core of the Action of Incretin and Glucagon-Based Anti-Obesity Drugs

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Authors

FVFrancesc VillarroyaMPMarion PeyrouMGMarta Giralt

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Overview

Review highlights adipose tissue's role in incretin-based drug effects on obesity, suggesting metabolic benefits.

Key Points

  • Incretin-based anti-obesity drugs significantly alter adipose tissue properties and improve systemic health.
  • Evidence shows major changes in metabolism and inflammatory states of adipose tissue associated with these drugs.
  • Adipose tissue thermogenic plasticity is promoted by incretin-based therapies, enhancing weight loss outcomes.
  • Research suggests that the properties of adipose tissue are crucial in achieving obesity-related health improvements.

Cite This Study

Villarroya et al. (2025) studied this question.

synapsesocial.com/papers/68c23a2cb210217d6477f2dahttps://doi.org/10.1007/s13679-025-00660-w
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