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September 5, 2025Frontiers in OncologyOpen Access

Case Report: Genomic insights and personalized treatment in dual primary esophageal squamous cell carcinoma and gastric adenocarcinoma

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Authors

CMChuanwang MiaoYGYaning GuoHYHui‐Li Yang

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Overview

Case report demonstrating personalized treatment via genetic profiling in dual malignancies, highlighting key outcomes.

Key Points

  • Genomic analysis revealed independent tumor origins in a patient with dual cancers, guiding treatment.
  • The patient showed stable disease after receiving chemoradiotherapy and immunotherapy without recurrence.
  • Next-generation sequencing identified chromosomal amplifications and deletions associated with each cancer type.
  • This case emphasizes the potential for precision treatment based on genetic alterations in complex cancer cases.

Cite This Study

Miao et al. (2025) studied this question.

synapsesocial.com/papers/68c23a2cb210217d6477f1fchttps://doi.org/10.3389/fonc.2025.1625063
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