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September 5, 2025Frontiers in OncologyOpen Access

Effectiveness and safety profile of chidamide as maintenance therapy for peripheral T-cell lymphoma: a multicenter real-world study

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Authors

WJWenjing JiangXZXiyuan ZhangWSWei Song

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Overview

Real-world analysis demonstrates improved outcomes for patients with peripheral T-cell lymphoma, indicating the effectiveness of chidamide in maintenance therapy.

Key Points

  • Chidamide as maintenance therapy improved prognosis in patients with peripheral T-cell lymphoma.
  • Overall survival rate was not achieved, while the median progression-free survival was 54.8 months.
  • Patients attaining complete response showed significantly better outcomes in progression-free survival.
  • The safety profile included a 20.3% rate of severe adverse events, notably neutropenia.

Cite This Study

Jiang et al. (2025) studied this question.

synapsesocial.com/papers/68c23a2cb210217d6477f17chttps://doi.org/10.3389/fonc.2025.1596270
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