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September 5, 2025NanomaterialsOpen Access

Current Status and Future Aspects of Gadolinium Oxide Nanoparticles as Positive Magnetic Resonance Imaging Contrast Agents

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Authors

EMEndale MulugetaTTTirusew TegafawYLYing Liu

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Overview

This review evaluates gadolinium oxide nanoparticles as T1 MRI contrast agents, highlighting current challenges and future developments.

Key Points

  • Gadolinium oxide nanoparticles exhibit promising properties as T1 MRI contrast agents, yet significant toxicity assessments are necessary.
  • Their relaxivities notably surpass those of approved gadolinium chelates, showing robust contrast enhancement in animal studies.
  • This review covers synthesis, characterization, and in vivo applications of these nanoparticles, along with their toxicity profiles.
  • Future directions emphasize the need for advances in formulation for renal excretion, aiming for clinical application.

Cite This Study

Mulugeta et al. (2025) studied this question.

synapsesocial.com/papers/68c239e5b210217d6477e829https://doi.org/10.3390/nano15171340
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