Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 5, 2025EndocrineOpen Access

Adrenal function, morbidity and mortality in patients with COVID-19

View Full Paper
Ask AI
Bookmark
Share

Authors

KRKarina RozenfeldESElad ShemeshEIElena Izkhakov

Discussion

Loading...

Member takes

Overview

Retrospective analysis shows adrenal insufficiency is rare in COVID-19 patients, suggesting no link to dexamethasone treatment.

Key Points

  • Adrenal insufficiency is diagnosed in only 3.5-7% of COVID-19 patients, correlating with disease severity.
  • Serum free cortisol is a strong independent predictor for in-hospital mortality and the need for ventilation support.
  • Dexamethasone treatment shows no association with the incidence of adrenal insufficiency in COVID-19 patients.
  • Overall, serum free cortisol emerges as a superior biomarker compared to traditional clinical parameters for COVID-19 prognosis.

Cite This Study

Rozenfeld et al. (2025) studied this question.

synapsesocial.com/papers/68c239e5b210217d6477e7d8https://doi.org/10.1007/s12020-025-04401-w
View Full Paper
Ask AI
Bookmark
Share