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September 5, 2025Medicine Science | International Medical JournalOpen Access

Prognostic significance of FIB-4 versus FIB-5 in non-ST-segment-elevation acute coronary syndrome

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Authors

ÖÇÖzge Çetinarslan

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Overview

Retrospective cohort analyzed FIB-4 and FIB-5 in 155 NSTE-ACS patients, indicating FIB-4 predicts outcomes better.

Key Points

  • FIB-4≥3.25 triples the risk of major adverse events in NSTE-ACS patients, highlighting its significance in prognostic assessment.
  • During follow-up, the composite end-point occurred in 64.5% of patients with high FIB-4, compared to 36.3% with low FIB-4 (p=0.006).
  • Multivariable logistic regression confirmed FIB-4≥3.25 as an independent predictor (adjusted OR 3.14), outperforming the FIB-5 score in risk assessment.
  • FIB-5 did not predict composite outcomes or individual components, indicating its limited utility compared to FIB-4.

Cite This Study

Özge Çetinarslan (2025) studied this question.

synapsesocial.com/papers/68c239e5b210217d6477e393https://doi.org/10.5455/medscience.2025.05.127
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