Assessing the Prognostic Accuracy of the PSS, pSOFA, and SIRS for In-Hospital Mortality in Children with Suspected Infection in Non-ICU Settings: A Multicenter Retrospective Study

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Retrospective study assesses mortality risk in pediatric patients with suspected infections, suggesting implications for clinical stratification.

PSS, pSOFA, and SIRS scores were evaluated for predicting in-hospital mortality in pediatric sepsis patients.
The PSS showed an AUROC of 0.756, indicating a modest improvement over SIRS but lower than pSOFA's 0.845.
Among 965 participants, the overall mortality was 1.1%, with significant cases requiring PICU transfer for sepsis.
Statistically, no significant differences were found among the three scoring systems, suggesting limited predictive advantage.

Liu et al. (2025) studied this question.

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Retrospective study assesses mortality risk in pediatric patients with suspected infections, suggesting implications for clinical stratification.