September 5, 2025European Heart JournalOpen Access

Surgical left atrial appendage occlusion in valvular heart disease without atrial fibrillation: the OPINION trial

View Full Paper

Ask AI

Bookmark

Authors

XYXin YuanZhengzhou University FJFan JuChinese Academy of Medical Sciences & Peking Union Medical College HWHengchao WuChinese Academy of Medical Sciences & Peking Union Medical College

Discussion

Member takes

Implication

Randomized trial evaluates prophylactic SLAAO reducing thrombo-embolic events in valvular heart disease patients, suggesting minimal impact on primary outcomes.

Key Points

SLAAO did not significantly reduce thrombo-embolic events after valvular surgery at 1-year follow-up.
The primary outcome occurred in 6.9% of SLAAO patients compared to 8.2% in the control group (hazard ratio 0.83).
Multicentre, open-label, randomized trial was conducted across three cardiac surgery centers in China.
Routine prophylactic left atrial appendage closure may not be necessary for non-AF patients with CHA₂DS₂-VASc ≥2.

Cite This Study

Yuan et al. (2025) studied this question.

synapsesocial.com/papers/68c239a3b210217d6477d616 https://doi.org/10.1093/eurheartj/ehaf674

View Full Paper

Ask AI

Bookmark

Implication

Randomized trial evaluates prophylactic SLAAO reducing thrombo-embolic events in valvular heart disease patients, suggesting minimal impact on primary outcomes.

Surgical left atrial appendage occlusion in valvular heart disease without atrial fibrillation: the OPINION trial

Discussion

Member takes

Implication

Key Points

Cite This Study

Surgical left atrial appendage occlusion in valvular heart disease without atrial fibrillation: the OPINION trial

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider