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September 5, 2025Cardiovascular DiabetologyOpen Access

Association between dynamic changes in the triglyceride-glucose index and prognosis in patients with acute ST-segment elevation myocardial infarction

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Authors

HJHaiyan JiaWZWeifeng ZhangSJShengqi Jia

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Overview

Retrospective cohort study identifies TyG trajectories that predict cardiovascular outcomes in patients, highlighting their role in secondary prevention.

Key Points

  • The rapid decline in TyG index is linked with significantly lower major adverse cardiovascular events over five years.
  • Among 1,092 STEMI patients, distinct TyG index trajectories were identified using Group-Based Trajectory Modeling.
  • The Cox regression analysis reveals that TyG trajectory independently predicts long-term cardiovascular outcomes.
  • Persistently high TyG trajectories indicate an elevated risk, suggesting they may be critical for targeting secondary prevention.

Cite This Study

Jia et al. (2025) studied this question.

synapsesocial.com/papers/68c239a3b210217d6477d4b2https://doi.org/10.1186/s12933-025-02858-7
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The triglyceride-glucose index is associated with coronary plaque features and clinical outcomes in patients with ST-segment elevation myocardial infarction2025 · 4 citations
  2. 2The association between triglyceride–glucose index and the recurrence of myocardial infarction in young patients with previous coronary heart disease2025 · 1 citations
  3. 3Prognostic value of the triglyceride–glucose index in patients with premature acute coronary syndrome2026
  4. 4Triglyceride glucose index in patients with acute coronary syndrome undergoing percutaneous coronary intervention predicts cardiovascular events: a cohort study2025 · 5 citations
  5. 5Correlation of the triglyceride-glucose index with major adverse cardiovascular events in type 2 diabetes mellitus patients with acute myocardial infarction combined with HFpEF2025 · 2 citations