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September 5, 2025International Journal of Clinical PharmacyOpen Access

Beyond black boxes: using explainable causal artificial intelligence to separate signal from noise in pharmacovigilance

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Authors

RFRenato Ferreira‐da‐SilvaRCRicardo Cruz‐CorreiaIRInês Ribeiro‐Vaz

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Overview

Commentary highlights the potential of explainable AI to improve signal detection in pharmacovigilance, suggesting a shift towards causally informed models.

Key Points

  • Explainable AI can improve signal detection in pharmacovigilance, enhancing transparency and reliability.
  • Causal AI methods face challenges but promise more interpretable outputs compared to traditional machine learning models.
  • The integration of causal inference in AI workflows is essential for scientifically credible pharmacovigilance applications.
  • Developing benchmark datasets is crucial for evaluating AI models against clinical and regulatory standards.

Cite This Study

Ferreira‐da‐Silva et al. (2025) studied this question.

synapsesocial.com/papers/68c239a3b210217d6477d351https://doi.org/10.1007/s11096-025-02004-z
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