Visual Cognitive Assessment Test correlates with brain amyloid status in Alzheimer's disease-related mild cognitive impairment

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Cross-sectional analysis reveals VCAT detects amyloid-positive patients better than MoCA, suggesting diagnostic potential.

VCAT correlates significantly with PET-detected amyloid deposition in MCI patients, indicating its diagnostic utility.
Compared to MoCA, VCAT achieved higher accuracy for identifying amyloid-positive MCI with an AUC of 0.830.
The study utilized baseline data registration, VCAT, MoCA, and MRI scans among 370 participants from a university hospital.
Full VCAT versions are necessary for effective Aβ detection, as abbreviated versions showed reduced efficacy.

Su et al. (2025) studied this question.

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