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September 5, 2025Clinics and PracticeOpen Access

Implantable Cardioverter–Defibrillator Therapies Following Generator Replacements—Long-Term Remote Monitoring Data

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Authors

MDMaciej DyrbuśŁPŁukasz PykaAKAnna Kurek

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Overview

Analysis reveals arrhythmic risks and mortality rates in patients post ICD/CRT-D replacement, suggesting new stratification models are necessary.

Key Points

  • Among 134 patients monitored post-device replacement, 32.1% experienced appropriate ICD therapies and 38.0% reported all-cause mortality rates.
  • Findings indicate that predictors of mortality included appropriate antitachycardia pacing, reduced LVEF, and no history of myocardial infarction.
  • Kaplan–Meier estimates and Cox proportional hazards regression were employed to assess long-term outcomes and treatment predictors over a median follow-up of 3 years.
  • Improvement in LVEF was not shown to enhance survival or reduce device therapy interventions, calling for improved stratification models.

Cite This Study

Dyrbuś et al. (2025) studied this question.

synapsesocial.com/papers/68c239a3b210217d6477cebchttps://doi.org/10.3390/clinpract15090160
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Post-defibrillation survival: a measure of ICD and CRT-D effectiveness2026
  2. 2Dutch outcome in implantable cardioverter-defibrillator therapy extended follow up do it xl long term outcomes in a large primary prevention population2026
  3. 3Predictors of Atrial High‐Rate Episodes and Inappropriate Device Therapy in Implantable Cardioverter Defibrillators2025
  4. 4Identifying the vulnerable: navigating the predictors of implantable cardioverter defibrillator (ICD) therapy in the moderately reduced ejection fraction (EF) cohort2026 · 1 citations
  5. 5Survival of patients undergoing cardiac resynchronization therapy with or without defibrillator: the RESET-CRT project2022 · 52 citations