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September 5, 2025Open Access

Demographic Profile of Oral Squamous Cell Carcinoma Patients Treated with Radiation Therapy: A Retrospective Observational Study at a Johannesburg Academic Hospital (2014–2019), South Africa

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Authors

GFGal FellerDMDaniel MmerekiFMFarzana Mahomed

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Overview

Retrospective analysis reveals high prevalence of tobacco and alcohol use in OSCC patients, highlighting radiation-related toxicities.

Key Points

  • Advanced-stage oral squamous cell carcinoma is common among older males, with notable high-risk behaviors.
  • Among 119 patients, 71% were male, with tobacco usage reported in 94% of males and 66% of females.
  • The study employed a retrospective, cross-sectional design to analyze demographic and clinical features of patients.
  • High rates of radiation-induced toxicities were observed, particularly in patients receiving concurrent chemoradiotherapy.

Cite This Study

Feller et al. (2025) studied this question.

synapsesocial.com/papers/68c239a3b210217d6477ceadhttps://doi.org/10.21203/rs.3.rs-7338125/v1
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