Identification of Common Genes for Neuropathic Pain and Parkinson’s Disease Based on Bioinformatics Analysis and Their Potential Value in the Diagnosis of Neuropathic Pain
Bioinformatics analysis identifies three co-hub genes linked to parkinson's disease and neuropathic pain, suggesting diagnostic implications.
Key Points
Three co-hub genes were identified that exhibit diagnostic accuracy for both parkinson's disease and neuropathic pain.
Differential infiltration of Tregs and Th2 cells was observed between disease and control groups, indicating immune response involvement.
Analysis of co-hub genes revealed their expression in neurons and astrocytes, highlighting their potential role in neuropathic pain and parkinson's disease.
Eight miRNAs targeting co-hub genes were predicted, which may interact with the molecular mechanisms underlying these conditions.