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September 5, 2025Sexually Transmitted Infections

Prevalence of antenatal syphilis remains positively associated with HIV in South African districts

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TKTendesayi KufaNSNosipho ShangaseAPAdrian Puren

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Overview

Ecological analysis reveals a positive correlation between HIV and syphilis prevalence, suggesting increased sexual network connectivity.

Key Points

  • The increased prevalence of syphilis is positively associated with higher HIV rates in South African districts.
  • In 2022, the correlation coefficient (Rho) between HIV and syphilis prevalence was found to be 0.42, significant at p=0.0018.
  • Analysis of data from South Africa's 2022 Antenatal HIV Sentinel Survey showed notable increases in syphilis from 0.1% in 2010 to 5.2% in 2022.
  • Findings support the idea of increased sexual network connectivity in districts experiencing high syphilis rates.

Cite This Study

Kufa et al. (2025) studied this question.

synapsesocial.com/papers/68c239a3b210217d6477cb63https://doi.org/10.1136/sextrans-2025-056650
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