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September 5, 2025New England Journal of Medicine

Home-Based Care for Hypertension in Rural South Africa

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Authors

MSMark J. SiednerNMNombulelo MagulaLMLusanda Mazibuko

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Overview

Randomized controlled trial found home-based care reduced systolic blood pressure in hypertension patients, suggesting benefits over standard care.

Key Points

  • Home-based care significantly lowered mean systolic blood pressure at 6 months compared to standard care.
  • The CHW group's systolic blood pressure was reduced by 7.9 mm Hg, while the enhanced CHW group saw a 9.1 mm Hg reduction.
  • 76.9% of participants in the CHW group achieved hypertension control at 6 months, versus 57.6% in standard care.
  • Retention in care exceeded 95% in both the CHW and enhanced CHW groups, indicating high compliance and support.

Cite This Study

Siedner et al. (2025) studied this question.

synapsesocial.com/papers/68c239a3b210217d6477cab7https://doi.org/10.1056/nejmoa2509958
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Quality of Care for Hypertension in Primary Health Care in South Africa: Cross-Sectional Feasibility Study2025 · 1 citations
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  5. 5Community-based Approaches to improve hypertension treatment among people living with HIV2025