September 5, 2025CureusOpen Access

Association Between Gastroesophageal Reflux Disease and Chronic Respiratory Symptoms: A Systematic Review of Recent Clinical Evidence and Therapeutic Implications

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Discussion

Systematic review reports significant links between gastroesophageal reflux disease and chronic cough, suggesting treatment integration.

GERD is associated with chronic respiratory symptoms, impacting conditions like asthma and COPD.
Acid-suppressive therapies, notably proton pump inhibitors, improve symptoms in patients with GERD-related respiratory issues.
Non-pharmacological interventions like diaphragmatic breathing also provide benefits for patients experiencing chronic cough from GERD.
While the evidence shows correlation, establishing definitive causality remains complex and calls for integrated treatment approaches.

Ahmed et al. (2025) studied this question.

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