September 5, 2025Frontiers in MedicineOpen Access

Expression of cyclooxygenase-2 and smooth muscle actin biomarkers in different subtypes of basal cell carcinoma

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Discussion

In vitro analysis reveals COX-2 as a prognostic marker linked to invasion depth in basal cell carcinoma, suggesting targeted treatment strategies.

COX-2 expression significantly correlated with tumor invasion depth and recurrence in basal cell carcinoma.
SMA expression was observed in 88.2% of cases, while COX-2 expression was found in 21.6% of analyzed samples.
Immunohistochemistry was performed on various basal cell carcinoma subtypes, evaluating clinical and histological characteristics.
Results suggest potential targeted diagnostic strategies based on COX-2 as a prognostic marker for BCC.

Ilanlou et al. (2025) studied this question.

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September 5, 2025Frontiers in MedicineOpen Access

View Full Paper

Ask AI

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Authors

In vitro analysis reveals COX-2 as a prognostic marker linked to invasion depth in basal cell carcinoma, suggesting targeted treatment strategies.

COX-2 expression significantly correlated with tumor invasion depth and recurrence in basal cell carcinoma.
SMA expression was observed in 88.2% of cases, while COX-2 expression was found in 21.6% of analyzed samples.
Immunohistochemistry was performed on various basal cell carcinoma subtypes, evaluating clinical and histological characteristics.
Results suggest potential targeted diagnostic strategies based on COX-2 as a prognostic marker for BCC.

Ilanlou et al. (2025) studied this question.

View Full Paper

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Bookmark