Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: evidence from retrospective study
This retrospective study shows clinical pharmacists improved medication adherence and reduced PIMs in older adults, indicating valuable collaboration in pharmaceutical care.
Key Points
Clinical pharmacist interventions reduced the total number of medications by 6.6%, indicating effective medication optimization.
After medication reviews, potentially inappropriate medications decreased by 29.5% based on the Priscus List, improving safety for elderly patients.
Drug-drug interactions were significantly reduced, with X-type DDIs dropping by 75.8% and D-type DDIs by 56.9%, enhancing medication efficacy.
Adherence to treatment guidelines improved significantly, increasing from 3.3%-13.2% to 50.0%-72.6%, suggesting better long-term management.