September 5, 2025Frontiers in ImmunologyOpen Access

Functional interaction between immune checkpoints and lipid metabolism in the development of arteriosclerosis obliterans

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Analysis reveals immune checkpoints influence lipid metabolism in arteriosclerosis obliterans, suggesting new therapeutic targets.

Immune checkpoints significantly affect lipid metabolism, which is crucial in the pathophysiology of arteriosclerosis obliterans.
Alterations in lipid metabolism are linked to chronic inflammation, contributing to the progression of arteriosclerosis obliterans.
Current treatments for arteriosclerosis obliterans underscore the need for novel therapeutic strategies targeting immune checkpoints.
Exploring the interplay between lipid metabolism and immune checkpoints could lead to innovative management approaches for arteriosclerosis obliterans.

Zhang et al. (2025) studied this question.

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