September 5, 2025World Journal of Biological Chemistry

CD47/SIRPα pathways: Functional diversity and molecular mechanisms

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The cd47/sirpα interaction plays a crucial role in regulating cellular functions, such as adhesion and apoptosis.
Increased cd47 expression in tumor cells facilitates evasion of the immune response, aiding tumor progression.
Anti-cd47 antibodies show promise in treating hematologic and solid tumors, indicating new therapeutic approaches.
Understanding the molecular mechanisms behind cd47/sirpα pathways can lead to enhanced cancer treatment strategies.

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Implication

This review explores the multifunctional roles of cell surface receptors in tumor cells, highlighting cd47/sirpα interactions and their potential therapeutic implications.

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Bhardwaj et al. (2025) studied this question.

synapsesocial.com/papers/68c23966b210217d6477c1f2 https://doi.org/10.4331/wjbc.v16.i3.108045

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Implication

This review explores the multifunctional roles of cell surface receptors in tumor cells, highlighting cd47/sirpα interactions and their potential therapeutic implications.

CD47/SIRPα pathways: Functional diversity and molecular mechanisms

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Discussion

Implication

Cite This Study

CD47/SIRPα pathways: Functional diversity and molecular mechanisms

Key Points

Discussion

Implication

Cite This Study

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