Methanol Extract of Chrysophylum albidum Fruit Attenuates Dextran Sulfate Sodium-Induced Ulcerative Colitis

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Experimental model shows Chrysophylum albidum extract reduces inflammation in IBD, highlighting potential as a natural therapy.

Chrysophylum albidum extract significantly reduced inflammatory cell infiltration in DSS-induced colitis.
Administration of the extract improved levels of MDA, nitrite, TNF-α, and IL-6, with p<0.05 significance.
Observed effects were attributed to antioxidant and anti-inflammatory mechanisms of the methanol extract.
Increased MUC-2 expression was noted in colonic tissues after CAFÉ treatment in male Wistar rats.

Omolaso et al. (2025) studied this question.

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