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September 5, 2025Mediators of InflammationOpen Access

Electroacupuncture Attenuates Hepatic Ischemia‐Reperfusion Injury by Modulating the Esr1/TAK1–JNK/p38 Signaling Pathway in Rats

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Authors

XFXiaofang FanWGWei GuoXYXiaodan Yang

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Overview

This study demonstrates that electroacupuncture lowers hepatic ischemia-reperfusion injury markers in rats, suggesting a role for Esr1 and TAK1 in this process.

Key Points

  • Electroacupuncture treatment significantly reduced serum ALT and AST levels, indicating improved liver function.
  • Histological analysis showed decreased necrotic areas and apoptosis in electroacupuncture-treated liver tissues.
  • The study found that electroacupuncture inhibited the TAK1–JNK/p38 signaling pathway, leading to reduced hepatocyte apoptosis.
  • Findings indicate that electroacupuncture may serve as a therapeutic approach in managing hepatic ischemia-reperfusion injury.

Cite This Study

Fan et al. (2025) studied this question.

synapsesocial.com/papers/68c23966b210217d6477bc0ehttps://doi.org/10.1155/mi/4932970
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