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September 5, 2025International Journal of Community Medicine and Public HealthOpen Access

Combination of urinary lipoarabinomannan assay and GeneXpert MTB/RIF ultra enhances tuberculosis detection among HIV-infected individuals

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Authors

JOJared Mekenye OngwaeDODaniel OnguruSOSidney Ogolla

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Overview

Analytic cross-sectional study finds improved diagnostic accuracy of assays in HIV-positive individuals, suggesting better outcomes.

Key Points

  • FujiLAM and GeneXpert MTB/RIF Ultra significantly enhance tuberculosis diagnosis in HIV-positive patients.
  • Results showed GeneXpert had 90.5% sensitivity and 98.1% specificity, demonstrating high accuracy.
  • The study involved 372 adult participants and analyzed variations in assay sensitivity and specificity.
  • Combining urinary LAM and GeneXpert may lead to quicker treatment initiation and improved patient outcomes.

Cite This Study

Ongwae et al. (2025) studied this question.

synapsesocial.com/papers/68c23966b210217d6477ba57https://doi.org/10.18203/2394-6040.ijcmph20252828
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