Evaluation of Neutrophil-Lymphocyte Ratio in Early Diagnosis of Severe Acute Pancreatitis using the Computed Tomography Severity Index as Reference Standard

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Discussion

Cross-sectional study evaluates neutrophil-lymphocyte ratio in acute pancreatitis diagnosis, suggesting high sensitivity and specificity.

NLR shows high sensitivity of 91.11% for diagnosing severe acute pancreatitis, enabling early intervention.
Positive predictive value is 85.42%, indicating reliability in identifying true cases among patients with high NLR.
Negative predictive value was 93.22%, reflecting its effectiveness in ruling out severe cases in patients below the cut-off.
This method is non-invasive and reproducible, making it a promising tool for initial triage in acute pancreatitis.

Butt et al. (2025) studied this question.

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