September 5, 2025Journal of NephropathologyOpen Access

PKD1 gene rs7185040 polymorphism and progression of chronic kidney disease in patients with ADPKD

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Authors

AKAiswarya KosarajuSri Ramachandra Institute of Higher Education and Research SSSandhya SureshSri Ramachandra Institute of Higher Education and Research RERamprasad ElumalaiSri Ramachandra Institute of Higher Education and Research

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Implication

Case-control analysis reveals no significant association between PKD1 rs7185040 polymorphism and CKD progression in ADPKD, suggesting the need for further research.

Key Points

There was no significant association between the pkd1 polymorphism rs7185040 and chronic kidney disease progression.
A total of 102 ADPKD patients and 106 controls were analyzed using the χ2 association test for genotype distribution.
The study utilized the fluorescent resonance energy transfer (FRET)-based KASPar method for genotyping pkd1 tag SNP.
These findings highlight the complexity of genetic factors influencing CKD progression in ADPKD patients.

Cite This Study

Kosaraju et al. (2025) studied this question.

synapsesocial.com/papers/68c23965b210217d6477b4c1 https://doi.org/10.34172/jnp.2025.25553

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Implication

Case-control analysis reveals no significant association between PKD1 rs7185040 polymorphism and CKD progression in ADPKD, suggesting the need for further research.

PKD1 gene rs7185040 polymorphism and progression of chronic kidney disease in patients with ADPKD

Discussion

Member takes

Implication

Key Points

Cite This Study

PKD1 gene rs7185040 polymorphism and progression of chronic kidney disease in patients with ADPKD

Discussion

Member takes

Implication

Key Points

Cite This Study

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