Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
September 5, 2025International Journal of Molecular SciencesOpen Access

Association of Circulating miRNAs from the C19MC Cluster and IGF System with Macrosomia in Women with Gestational Diabetes Mellitus

View Full Paper
Ask AI
Bookmark
Share

Authors

MRMagalhi Robledo-ClementeJGJuan Carlos Silva GodínezMDMary Flor Díaz-Velázquez

Discussion

Loading...

Member takes

Overview

Cross-sectional analysis identifies associations between circulating micrornas and IGF markers in gestational diabetes cases, suggesting implications for fetal growth.

Key Points

  • Circulating C19MC miRNAs are dysregulated in gestational diabetes, correlating with IGF signaling and macrosomia.
  • Notable correlations were observed between miR-516a-5p and IGFBP-5, with r = 0.705; p < 0.001.
  • Differential expression of several miRNAs was particularly pronounced in large-for-gestational-age newborns.
  • Study outcomes support the potential for using miRNAs as early biomarkers for macrosomia risk in GDM pregnancies.

Cite This Study

Robledo-Clemente et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477b13ehttps://doi.org/10.3390/ijms26178367
View Full Paper
Ask AI
Bookmark
Share