This review highlights how extracellular vesicles influence immune responses and host interactions in intestinal protozoa.
Key Points
Extracellular vesicles are crucial for communication between intestinal protozoan parasites and their hosts, facilitating immune responses and pathogenesis.
Studies indicate that Giardia duodenalis EVs disrupt tight junctions and promote Th1 immune responses while Blastocystis sp. EVs modulate cytokines.
The review addresses the biogenesis and molecular cargo of parasite-derived extracellular vesicles linked to immune modulation.
Research suggests parasite-derived extracellular vesicles could serve as biomarkers and therapeutic agents, highlighting their potential in treating infections.