September 5, 2025Open Access

Is glucose-6-phosphate dehydrogenase deficiency associated with COVID-19 infection, severity, and death? A cohort study from the Brazilian Amazon

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No significant association exists between G6PD deficiency and COVID-19 infection or hospitalization.
The study evaluated 3,955 participants, reporting an odds ratio of 1.15 for infection with p = 0.6.
Logistic regression was used to assess associations while Cox models evaluated time-to-event outcomes.
Results highlight the importance of ethnic diversity in understanding health outcomes in high G6PD deficiency regions.

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Cohort study finds no link between G6PD deficiency and COVID-19 outcomes, suggesting diverse risk factors.

Dias et al. (2025) studied this question.

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