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September 5, 2025International Journal for Parasitology Drugs and Drug ResistanceOpen Access

Faecal egg count reduction test, deep amplicon sequencing of isotype-1 β-tubulin gene and in ovo larval development assay reveal susceptibility to benzimidazoles of porcine nematodes Oesophagostomum spp. and Ascaris suum in outdoor-reared pigs in Germany

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Authors

HFHannah R.M. FischerJKJürgen KrückenSFS. Fiedler

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Overview

This analysis reveals anthelmintic resistance in Oesophagostomum is absent, while Ascaris suum shows ambiguous FECRT results, suggesting careful interpretation is needed.

Key Points

  • The faecal egg count reduction test revealed no anthelmintic resistance in Oesophagostomum on German farms, indicating effective treatment.
  • Amplicon sequencing showed no β-tubulin gene polymorphisms linked to resistance in Oesophagostomum, reinforcing its susceptibility profile.
  • The in ovo larval development assay identified all tested populations of Ascaris suum as susceptible to benzimidazoles, indicating treatment efficacy.
  • However, interpretation of FECRT for Ascaris suum was complicated due to potential false positives from coprophagy among pigs.

Cite This Study

Fischer et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477a85dhttps://doi.org/10.1016/j.ijpddr.2025.100612
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