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September 5, 2025World Journal of Clinical Cases

Life-course management of gestational diabetes mellitus: A narrative review

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Authors

QLQiong LuoQNQiang Ni

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Overview

Narrative review synthesizes evidence on gestational diabetes management and maternal outcomes, suggesting lifestyle modifications and pharmacologic treatments.

Key Points

  • Gestational diabetes mellitus significantly increases a mother’s risk of developing type 2 diabetes up to tenfold, and this requires effective long-term management.
  • Emerging evidence shows that hyperglycemia before diagnosis can impair fetal programming via epigenetic mechanisms, indicating the need for early intervention.
  • The narrative review highlights the critical role of lifestyle modification in managing gestational diabetes, often supplemented with medications like insulin or metformin.
  • Future efforts should focus on early risk detection and culturally sensitive interventions to improve maternal-child outcomes and address the complexities of maternal health.

Cite This Study

Luo et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477a628https://doi.org/10.12998/wjcc.v13.i29.111096
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1EMERGING TRENDS IN THE MANAGEMENT OF GESTATIONAL DIABETES MELLITUS A NARRATIVE REVIEW2025
  2. 2From Molecular Insights to Clinical Management of Gestational Diabetes Mellitus—A Narrative Review2025
  3. 3Gestational Diabetes Mellitus: Efficacy of Non-Pharmacological Interventions for Management and Prevention2025 · 5 citations
  4. 4Gestational diabetes mellitus: course and adverse outcomes of pregnancy exemplified by the clinical case2025
  5. 5Approach to the patient after gestational diabetes mellitus: what's next?2026