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September 5, 2025Gene ExpressionOpen Access

Targeted Delivery of MicroRNA Sponge Short-hairpin RNA via Vir-inspired Biotechnical Vector: Enhancing Cancer Therapy

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Authors

HRHananeh RozbahaniAZAlireza ZangooieSMSeyed Mohsen Mirabdolhosseini

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Overview

This review demonstrates improved targeted delivery of microRNA sponges and short-hairpin RNAs in cancer therapy, suggesting Vir-inspired Biotechnical Vector may overcome existing challenges.

Key Points

  • VIBV enhances targeted delivery of microRNA sponges and short-hairpin RNAs, significantly improving cancer treatment efficacy.
  • The hybrid delivery system, with a spindle-shaped nanocore, addresses issues of stability and immune evasion in drug delivery.
  • By utilizing tumor-specific cues for therapeutic release, VIBV demonstrates precision in gene therapy against cancer.
  • This approach may offer personalized cancer therapies while also revealing the need for continued research and refinement.

Cite This Study

Rozbahani et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477a5e6https://doi.org/10.14218/ge.2025.00042
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