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September 5, 2025Frontiers in Cell and Developmental BiologyOpen Access

Reprogramming cancer immunity with next-generation combination therapies

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Authors

NKNikolaos C. KyriakidisCECarolina E. EcheverríaJBJhommara Bautista

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Overview

This review highlights advances in immunotherapy methods and combination strategies in cancer treatments, suggesting personalized approaches may enhance outcomes.

Key Points

  • Next-generation cancer immunotherapy aims to overcome resistance by targeting multiple immune regulation layers.
  • Combination strategies integrating immune checkpoint inhibitors and cytokines have shown potential in enhancing treatment efficacy.
  • Biomarker-guided approaches are critical for personalizing immunotherapies and mitigating adverse events in patients.
  • Emerging technologies like AI and microbiome-targeted interventions could reshape the future of cancer treatment.

Cite This Study

Kyriakidis et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477a474https://doi.org/10.3389/fcell.2025.1652047
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