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September 5, 2025Frontiers in PsychiatryOpen Access

Nonlinear association between TyG-related Indices and motoric cognitive risk syndrome in depressive individuals: evidence from the CHARLS study

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Authors

ZWZhao WeiCLChao LiZLZ. G. Liu

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Overview

Observational analysis examined TyG indices and MCR risk in older adults, indicating significant nonlinear associations.

Key Points

  • TyG-BMI shows a nonlinear association with motoric cognitive risk syndrome, impacting cognitive health.
  • Significant threshold identified at 276.05 for TyG-BMI, where below this risk increases significantly.
  • Logistic regression was used to assess the relationship between TyG indices and MCR in 5,657 participants.
  • Results suggest that TyG-BMI may be a valuable biomarker for early detection of cognitive decline in depressive individuals.

Cite This Study

Wei et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d6477a460https://doi.org/10.3389/fpsyt.2025.1622973
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