Editorial reviews recent advances of metformin in type 2 diabetes and its potential for repurposing, indicating its multifaceted benefits.
Key Points
Metformin has shown beneficial effects on various noncommunicable diseases, particularly type 2 diabetes and obesity.
A systematic review revealed that metformin improves symptoms and quality of life in patients with knee osteoarthritis linked to impaired glucose tolerance.
The research topic combines original articles and studies that include randomized controlled trials and preclinical models demonstrating metformin's potential applications.
Caution is advised in using metformin for specific conditions like age-related macular degeneration, which may present risks in animal models.