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September 5, 2025PeerJOpen Access

Outcomes of stereotactic body radiotherapy for unresectable cholangiocarcinoma: a meta-analysis and systematic review

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Authors

PLPeng LiuHYHaiyan YeLSLijun Song

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Overview

Meta-analysis reveals SBRT improves overall survival and disease control rates in cholangiocarcinoma, suggesting it as a safe option.

Key Points

  • SBRT for unresectable cholangiocarcinoma indicates a pooled median overall survival of 13.4 months, suggesting effectiveness.
  • Pooled 1-year overall survival and disease control rates stand at 58.7% and 84.7% respectively, indicating promising outcomes.
  • The analysis involved thirteen studies with 366 patients, underscoring the robustness of findings regarding SBRT and cholangiocarcinoma.
  • Highlights the need for further research comparing SBRT with other treatments to fully establish its role in the management of cholangiocarcinoma.

Cite This Study

Liu et al. (2025) studied this question.

synapsesocial.com/papers/68c23922b210217d64779ecchttps://doi.org/10.7717/peerj.19909
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Stereotactic Body Radiotherapy of Colorectal Cancer Oligometastases to the Liver: Three Years Follow-Up2025
  2. 2From protocol to practice: long-Term outcomes of single-Fraction stereotactic body radiotherapy for primary non-Small cell lung cancer2025
  3. 3A monocentric retrospective analysis of 10‑year overall survival after stereotactic body radiotherapy for medically inoperable non‑small cell lung cancer2025
  4. 4Stereotactic body radiation therapy for early-stage non-small cell lung cancer: a single-institutional retrospective analysis of outcomes and prognostic factors2025
  5. 5Empiric stereotactic body radiotherapy for presumed early-stage lung cancer2025 · 1 citations