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September 5, 2025Discover Viruses.Open Access

A systematic review and modelling insights of factors impacting measles vaccine effectiveness, efficacy and immunogenicity

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Authors

SGSamiran GhoshDKDivya KapparaNMNabanita Majumder

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Overview

Systematic review uncovers factors impacting measles vaccine efficacy in children, suggesting targeted interventions.

Key Points

  • Malnutrition significantly decreases measles vaccine effectiveness, with evidence from extensive cohort studies.
  • The review included 48 articles analyzing vaccine performance in 172,464 children aged 0-15 years.
  • Regression analysis and modelling simulations reveal key factors affecting measles vaccine outcomes, including genetic variants and chemotherapy.
  • Addressing malnutrition and other determinants is crucial for improving measles elimination efforts globally.

Cite This Study

Ghosh et al. (2025) studied this question.

synapsesocial.com/papers/68c238d2b210217d64779c32https://doi.org/10.1007/s44370-025-00027-8
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