September 5, 2025FEMS Microbiology ReviewsOpen Access

Impact of bacterial vaginosis on sexually transmitted viral infections: a bacterial point of view

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Review explores the role of bacterial factors in influencing susceptibility to STIs, highlighting unique risk pathways.

Bacterial vaginosis significantly increases the risk of sexually transmitted infections, including HIV-1, due to changes in the vaginal microbiota.
The review identifies key bacterial contributors like Gardnerella vaginalis that negatively impact vaginal health, with implications for STIs.
Analysis of bacterial virulence factors reveals how secreted proteins and biofilm formation enhance susceptibility to viral infections.
Antimicrobial resistance in BV-associated bacteria poses a challenge for treatment, highlighting the need for new therapeutic strategies.

Segui‐Perez et al. (2025) studied this question.

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