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September 5, 2025Technology in Cancer Research & TreatmentOpen Access

Harnessing the Gut Microbiome in Cancer Immunotherapy: Mechanisms, Challenges, and Routes to Personalized Medicine—A Systematic Review

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Authors

ADAmir DayhimiKJKimia JaziABAsiye Bigdeli

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Overview

Systematic review reveals probiotics improve immune responses and enhance the efficacy of immunotherapy.

Key Points

  • Probiotics enhance immune responses, improving the efficacy of immunotherapy for cancer patients.
  • Clinical and preclinical studies indicate that probiotics can increase CD8+ T-cell activity with immunotherapy.
  • Challenges such as treatment resistance and drug delivery must be tackled to integrate probiotics effectively.
  • Personalized probiotic strategies tailored to individual microbiota hold promise for optimizing treatment outcomes.

Cite This Study

Dayhimi et al. (2025) studied this question.

synapsesocial.com/papers/68c238d2b210217d64779b8ehttps://doi.org/10.1177/15330338251365700
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