Case report reveals immune dysregulation and markers of T cell exhaustion in an SLE patient, highlighting the need for careful immune monitoring during recovery.
Key Points
Increased exhaustion markers like PD-1 and Tim-3 were observed in T cells during the recovery phase.
A 42-year-old SLE patient developed infective endocarditis post-splenectomy, leading to valve replacement surgery.
Marked immune dysregulation in SLE patients significantly increases infection susceptibility, especially after surgical procedures.
Monitoring immune cell dynamics is crucial for managing treatment strategies and improving outcomes in SLE patients.